ObjectivesThe NCCN guidelines recommend that the addition of bevacizumab should be considered in metastatic breast cancers in some circumstances, but there are no recommendations for the similar antiangiogenic drug apatinib.The aim of this study was to evaluate the safety and efficacy of apatinib in metastatic breast cancer patients pretreated with
In recent years heterocyclic compounds analogues and derivatives have attracted wide attention due to their useful biological and pharmacological properties.Benzothiazole is among the usually occurring heterocyclic nuclei in many marine as well as natural plant products.Benzothiazole is a privileged bicyclic ring THINNING HAIR TREAT KIT system with
Abstract As natural predators, owls fly with astonishing stealth due to the serrated feather morphology that produces advantageous flow characteristics.Traditionally, these serrations are tailored for airfoil edges with simple two-dimensional patterns, limiting their effect on noise reduction while negotiating tradeoffs in aerodynamic performance.C
The kinetics of recovery from neuromuscular fatigue resulting from exercise time trials (TTs) of different durations are not well-known.The aim of this study was to determine if TTs of three different durations would result in different short-term recovery in maximal voluntary contraction (MVC) and evoked peak forces.Twelve trained subjects perform
This paper proposes an underactuated grippers mechanism that grasps and pulls in different types of objects.These two movements are generated by only a single actuator while two independent actuators are used in conventional grippers.To demonstrate this principle, we have developed two kinds of gripper by different driving systems: one is driven by